Quantitative screening of genes regulating tryptophan hydroxylase transcription in Caenorhabditis elegans using microfluidics and an adaptive algorithm

Research published in Integrative Biology by Hyewon Lee, Matthew M. Crane, Yun Zhang and Hang Lu at the Georgia Institute of Technology and Harvard University (Integr. Biol., 2013, 5, 372-380) recently published that tridecafluoro-1,1,2,2-tetrahydrooctyl-1-trichlorosilane (T2492) from UCT Specialties (United Chemical Technologies) was used in research developing a quantitative genetic screening process based on a simple adaptive algorithm using a single-layer multifluidic device. Conventional UV photolithography was used to transfer microarray features onto the transparency. The T2492 kept the PDMS from adhering to the masters. The resultant PDMS layer was cut into shape, punched for holes and bonded onto a cover slip to make complete devices.

UCT Specialties continues to manufacture high quality specialty silanes, silicones, catalysts and coatings for a vast variety of manufacturing markets. This expertise, coupled with our excellence in the Solid Phase Extraction chromatography markets demonstrates UCT's leadership for all your silicon related chemistry products.