UCT always proudly supports regional meetings for Forensic Toxicologists. At this years Fall meeting of the Southwestern Association of Toxicologists (SAT) held in Norman, OK, UCT will be represented by Andrew Johansen. Andrew will be on hand throughout the meeting to discuss UCT methods, applications and products for use in the field of Forensic Toxicology. UCT is recognized for developing one of the first SPE methodologies for use with Spice Drugs and metabolites in blood and urine. Methods for analysis of bathsalts are also available. Please visit Andrew at the UCT booth to learn more about Clean Screen, Xcel and FASt range of technologies as well as our derivatizing reagents and manifolds for sample preparation.
Showing posts with label clean screen. Show all posts
Showing posts with label clean screen. Show all posts
Monday, October 1, 2012
Saturday, September 22, 2012
UCT Xcel I and Xcel II SPE columns, Hydrocodone
It has been recognized by forensic toxicology laboratories around the world that the abuse of prescription opioids for non-medical use has been on the rise over the past decade. The most commonly abused opioid is hydrocodone, a frequently prescribed pain medication. Laboratories have been requesting a sample prep column that would offer a rapid, efficient and reproducible methodology. UCT has responded with Xcel I and II SPE columns.
In a study recently published in Journal of Analytical Toxicology (September (2012;36:507–514)) Sandra Valtier and Vikhyat S. Bebarta of Lackland Air force Base, TX, demonstrated the use of the Xcel I column to determine the metabolites of hydrocodone i.e. hydromorphone, norhydrocodone in human urine. Their study describes the excretion profile of hydrocodone, hydromorphone and norhydrocodone in urine following a single dose (10 mg) administration of the drug to human subjects and presents a validated liquid chromatography– tandem mass spectrometry method for analysis of the drug and its metabolites. By showing that a LOQ was 5 ng/mL and LOD was 2.5 ng/mL for hydrocodone and norhydrocodone, and 5 ng/mL for hydromorphone were achievable through the use of Xcel I phase, it demonstrates how effective this SPE sorbent is in analyzing urine for these opiates.
UCT proudly stands behind its support of laboratories facing the increasing number of abused drugs by having a superior portfolio of SPE sorbents under the Clean Screen® banner. This line also includes the CSDAU and CSTHC range of sorbents, acknowledged around the world for their excellence in drug analysis.
Location:
Lackland AFB, TX 78226, USA
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