Gamma hydroxybutyrate and CUQAX156

In the field of Forensic Toxicology, analysts are often asked to analyze for Gamma hydroxybutyric acid (GHB) in cases where drug facilitated crimes may have occurred. With this in mind, UCT is proud to announce that a validated method has been published in the Journal of Chromatography B (879 (2011) 3752– 3758) using Clean-Up QAX SPE columns . This methodology, developed in collaboration with a major crime laboratory, employs UCT's CUQAX156 column to extract GHB from human urine. With the use of an anionic exchange sorbent, Dr. Jeff Hackett and Albert Elian were able to extract GHB from only 50 microliters of urine down a concentration of 50 nanograms per milliliter. The procedure, performed on LC-MS/MS, produced very low matrix effects (less than 6 percent). The samples extracted from the SPE are of the highest quality, allowing instruments to stay cleaner, longer and permitting many more analyses to be performed.