UCT Poster Presentation at SOFT 2012

Hair analysis for the presence of illicit drugs is becoming one of the most challenging types of forensic toxicological analysis. At this years SOFT meeting, Dr. Jeff Hackett will be presenting the results of a collaborative project involving Amphetamines and Synthetic Cathinones in hair samples (Poster P03). In this work, UCT's flagship sorbent Clean Screen DAU (CSDAU206) was employed to produce a highly efficient validated methodology for the simultaneous extraction of 4 Amphetamines (Amphetamine, methamphetamine, MDA, and  MDMA) and 9 Synthetic Cathinones (Butylone, ethylone, flephedrone, mephedrone, methylone, methedrone, methcathinone (4-MEC), methylenedioxypyravalerone (MDPV) and pyravalerone) from 10 mg samples of hair. This new methodology which involves a short base digestion time followed by SPE and LC-MS/MS permits limits of quantitation (LOQ) of 0.05 ng/ mg, and detection(LOD) of 0.1 ng/ mg of sample to be achieved with excellent recoveries (greater than 95%) and minimal matrix effects (less than 6%). This newer methodology demonstrates the strength of the DAU sorbent in the analysis of not only familiar drugs but new and novel ones as well.

Poster from SOFT using CSDAU on a wide range of drugs

Presented at last year’s SOFT meeting (Richmond, VA) was a poster: Reduce Your Backlog: Adopt a Single Solid Phase Extraction Approach to Detect and Quantify Basic, Acidic/Neutral, Sympathomometic Amines, and Cocaine/Metabolites using Mini-Bore Fast GC/MS by Daniel D Baker IV, Franklin County Coroners Laboratory Ohio, that demonstrates the power and versatility of UCT's world renowned CSDAU SPE column. Daniel showed that this sorbent is a valuable tool in maximizing efficiency and productivity in Coroners and Medical Examiner’s laboratories. In extracting a wide and diverse range of drugs (including 12 amphetamine type, 68 basic and 12 weak acid neutrals) from post mortem blood (1 mL), Daniel demonstrated how 1 single column can reduce difficulties encountered worldwide by Forensic Toxicologists involved in this area of analysis.

Analysis of Absinthe by Solid Phase Extraction and LC-MS/MS: A simple test for thujone concentration

In 2 weeks Michael J. Telepchak from UCT, Inc., will be attending the 9th Annual Csaba Horváth Symposium, April 28 – 29, 2009 at the Harford Convention Center, Hartford CT.

He will presenting a poster on Abisinthe authored by J. Hackett; M. J. Telepchak; M. J. Coyer. The poster is listed as P#01.