Thursday, August 25, 2011

2 papers appearing in JAT Special SOFT/TIAFT issue

UCT is honored to have two outstanding papers included in the Special Issue of Journal of Analytical Toxicology (JAT).

Forensic toxicologists are always being challenged to extract, confirm and quantify drugs and poisons in post mortem samples. The September issue of JAT features a publication by Dr. Thomas Rosano, D-ABFT who employed the UCT flagship sorbent (Clean Screen DAU) to perform this analysis. In his paper "Postmortem Drug Screening by Non-Targeted and Targeted Ultra-Performance Liquid Chromatography-Mass Spectrometry Technology" (JAT 35 (7) 411-23), Dr Rosano's team was able to analyze over 200 drugs on the Clean Screen DAU with excellent levels of efficiency. This developed methodology is indicative of the high quality of materials that the UCT is renowned for.

In a separate article, presented by Dr. James Watterson, D-ABFT and team, "Relative Distribution of Ketamine and Norketamine in Skeletal Tissues Following Various Periods of Decomposition" (JAT 35(7) 452-458), UCT's new and unique sorbent Clean Screen Xcel, was employed to extract, confirm, and quantify Ketamine and its metabolite from decomposing samples. It is common for toxicologists working in forensic laboratories to encounter such materials and this sorbent is shown to show excellent analytical characteristics

Monday, August 15, 2011

UCT at NEMC 2011 - August 15-19

As the world's premier SPE sorbent manufacturer, UCT Inc. is proud to announce its participation in the 2011 National Environmental Monitoring Conference (NEMC) held in Seattle WA. UCT will be represented by two outstanding members of the company, Don Shelly, Environmental Products Manager, and Bill Leavitt, Regional Sales Team Member. Don and Bill will be on hand all week to help, assist, and guide analysts with regard to products, applications and advice for enviromental analysis.

At this years meeting UCT will also be presenting 2 posters by Dr. Xiaoyan Wang, Environmental Specialist. The first study involves the highly efficient extraction of Haloacetic acids from water using GC-MS. This analysis employs UCT's speciality range of SPE cartridges as a robust alternative for facilities engaged in EPA method 552.1. UCT is always on the forefront of analytical methodologies in support of laboratories engaged in environmental analyses, and this application should be of great assistance them. The second of Dr. Wang's studies to be presented in poster format involves the extraction of pesticides, semi-volatiles, and PCB congeners using UCT's environmental range of cartridges to produce a methdology that is easily available to laboratories using standard GC-MS instrumentation.

Monday, August 1, 2011

False: conversion of Morphine to 6-MAM

Following reports in forensic-related media, regarding the conversion of Morphine (a commonly analyzed opiate in bio fluids by Crime Laboratories, Coroners, and Medical Examiners Facilities) to 6-Monoacetyl Morphine ( 6-MAM ), UCT Inc. is pleased to report that this issue does not occur in any of its products.

An independent Medical Examiner's Office recently carried out an experiment in which morphine (0.5 mg% to 5 mg% solutions) was heated (70 Deg C for 2 hours) in the presence of Acetylsalicylic acid (1mg% to 50 mg% solutions) in human urine. These experiments were carried out with and without ethyl alcohol being present. The internal standard employed in these studies was a deuterated analogue of 6-MAM. The samples were extracted using UCT's flagship sorbent Clean Screen DAU, after which they were derivatized to the Trimethylsilyl derivative and analyzed by gas chromatography-mass spectrometry. The outcome was that 6-MAM was not found in any samples.