In the area of forensic toxicology, probably the most requested drug analysis is that of THC. Toxicologists around the world are faced with analyzing whole blood samples for the presence of THC and its metabolites: Hydroxy-THC and Carboxy-THC. In performing this analysis, they can not only offer quantifiable concentrations but also an interpretation into impairment with regards to operating a motor vehicle. In order to perform this type of testing in a timely fashion, analysts are being asked to go to lower and lower concentrations in less and less time. UCT has always been recognized as producing the finest SPE sorbent in the world with this goal in mind, Clean Screen THC (CSTHC).
In a study accepted for publication by Journal of Forensic Toxicology and Pharmacology in December 2012, Dr Jeff Hackett (in conjunction with a major crime laboratory) employed this sorbent on board a robotic SPE workstation (Janus) to process the extraction of THC and its metabolites from whole blood samples. The robotic workstation permitted analysts to conduct other tasks while the SPE operation
was performed. The extraction process allowed concentrations of down to 0.5 ng/ mL of all of the cannabinoids to be detected by LC-MS/MS, with recoveries greater than 95%, and minimal matrix effects. The time savings by the robotic workstation over manual preparation was significant. This report offers another exciting avenue for the premier THC SPE sorbent in the area of analytical forensic toxicology.
In a study accepted for publication by Journal of Forensic Toxicology and Pharmacology in December 2012, Dr Jeff Hackett (in conjunction with a major crime laboratory) employed this sorbent on board a robotic SPE workstation (Janus) to process the extraction of THC and its metabolites from whole blood samples. The robotic workstation permitted analysts to conduct other tasks while the SPE operation
was performed. The extraction process allowed concentrations of down to 0.5 ng/ mL of all of the cannabinoids to be detected by LC-MS/MS, with recoveries greater than 95%, and minimal matrix effects. The time savings by the robotic workstation over manual preparation was significant. This report offers another exciting avenue for the premier THC SPE sorbent in the area of analytical forensic toxicology.
